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(2013) have described in vitro and in vivo biochemical effects after exposure to high concentrations of oxaliplatin, including neuronal activation of the purinoreceptor subtype 7, ROS and NO production, lipid peroxidation, loss of mitochondrial transmembrane potential and further apoptosis via caspase 3 activation

In order to further investigate the potential of three-pathway combinatorial biosynthesis of GSH, we compared utilization and conversion efficiency of amino acid precursors of engineered strain W303-1b/FGP with that of strain W303-1b/F in shake flask cultures

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References Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y